GDC-2394 Datasheet DC Chemicals

Description	GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC50s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation.
Cat.No	DC72265
Name	GDC-2394

Chemical Properties

CAS	2238822-07-4
Formula	C20H25N5O4S
MW	431.51
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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