PF-06291874（glucagon receptor antagonists-4） Datasheet DC Chemicals

Description	glucagon receptor antagonists-4 is a highly potent glucagon receptor antagonist.
Cat.No	DC10003
Name	PF-06291874（glucagon receptor antagonists-4）

Chemical Properties

CAS	1393124-08-7
Formula	C26H28F3N3O4
MW	503.5134
Storage	4°C for 1 year, -20°C for more than 2 years

References

[1]. Guzman-Perez A et al. The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical andpharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus. Bioorg Med Chem Lett, 2013 May 15, 23(10):3051-8. [2]. Esther C.Y. Lee et al. Identification of a novel conformationally constrained glucagon receptor antagonist. Bioorg Med Chem Lett, 2014 Feb 1, 24(3):839-44.

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