GSK-2945 Datasheet DC Chemicals

Description	GSK-2945 is a potent and selective small molecule Rev-Erbα agonist with EC50 of 50 nM, displays >1,000-fold selectivity over LXRα; inhibits LPS induction of IL-6 production and to upregulate expression of ABCA1 in human THP-1 cells; demonstrates in vivo bioavailability and orally active.
Cat.No	DC70458
Name	GSK-2945

Chemical Properties

CAS	1438071-12-5
Formula	C20H18CL2N2O2S
MW	421.336
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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