GSK205 derivative 16-8 Datasheet DC Chemicals
Description GSK205 derivative 16-8 is a specific small molecule dual-inhibitor of TRPV4 and TRPA1 with IC50 of 0.45 and 0.41 uM, respectively; displays no inhibitory potency toward TRPV1, TRPV2 and TRPV3; effectively attenuates formalin-evoked trigeminal irritant pain in model of acute pancreatitis.
Cat.No DC70451
Name GSK205 derivative 16-8

Chemical Properties

CAS 1532515-60-8
Formula C25H25N3S
MW 399.556
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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