GSK2850163 Datasheet DC Chemicals

Description	A novel potent IRE1α-selective kinase inhibitor that inhibits both the kinase and RNase activities of IRE1α with IC50 of 20 nM and 200 nM, respectively; binds to pIRE1α and inhibits XBP 1 splicing; only weakly inhibits Ron (IC50= 4.4 uM) and FGFR1 V561M (IC50=17 uM) in a panel of 284 kinases.
Cat.No	DC70125
Name	GSK2850163

Chemical Properties

CAS	2121989-91-9
Formula	C24H29CL2N3O
MW	446.41
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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