Lipid GVS-18-B6 Datasheet DC Chemicals
Description Lipid GVS-18-B6 is a silicon ether ionizable lipid for mRNA delivery. GVS-18-B6 showes particularly good liver specificity, with a liver-to-spleen EGFP signal ratio of 92:1. GVS-18-B6 also showes rapid tissue clearance within 6 hours of dosing.
Cat.No DC60564
Name Lipid GVS-18-B6

Chemical Properties

CAS
Formula C36H71NO3SI
MW 594.528
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

Silicon Ether Ionizable Lipids Enable Potent mRNA Lipid Nanoparticles with Rapid Tissue Clearance-ACS Nano-Apr 3, 2024-by Richard HollandKieu, James Heyes
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