hCAII-IN-8 Datasheet DC Chemicals
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Cat.No DC65499
Name hCAII-IN-8

Chemical Properties

CAS 952306-80-8
Formula C15H16N2O5S
MW 336.36
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：952306-80-8
Product Name：N-[3-(Aminosulfonyl)phenyl]-3,4-dimethoxybenzamide
Synonyms：hCAII-IN-8;Benzamide, N-​[3-​(aminosulfonyl)​phenyl]​-​3,​4-​dimethoxy-
EINEC:
Molecular Formula：C15H16N2O5S
Molecular Weight：336.36
Target: hCA II:0.18 μM (IC50)
In Vivo
In Vitro hCAII-IN-8 (compound 9) at a concentration of 100 μM for 24-48 hours showed no cytotoxicity in HEK-293 T cells, with cell viability exceeding 90% compared to the control[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Zahid Hussain, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264.
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