ICCB-19 hydrochloride Datasheet DC Chemicals

Description	ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy.
Cat.No	DC45531
Name	ICCB-19 hydrochloride

Chemical Properties

CAS	1803605-68-6
Formula	C12H22CLN3OS
MW	291.840580463409
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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