Ilginatinib maleate Datasheet DC Chemicals
Description Ilginatinib, also known as NS-018, is a selective JAK2 inhibitor. Ilginatinib preferentially inhibits CFU-GM colony formation by bone marrow mononuclear cells from high-risk myelodysplastic syndrome patients. NS-018 suppressed the phosphorylation of STAT3 in colony-forming cells from MDS patients. NS-018 reduces myeloma cell proliferation and suppresses osteolysis through inhibition of the JAK2 and Src signaling pathways.
Cat.No DC75507
Name Ilginatinib maleate

Chemical Properties

CAS 1354799-87-3
Formula C25H24FN7O4
MW 505.51
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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