IS20 Datasheet DC Chemicals

Description	IS20 is a Prokineticin receptor 1 (PKR1) agonist. IS20 diminishes Doxorubicin) mediated apoptosis and ROS production by activating Akt or MAPK pathways. IS20 protects the heart against Doxorubicin-induced cardiovascular toxicity and improves the survival rate and cardiac function in mouse models. IS20 does not alter the cytotoxicity and antitumor activity of acute DOX treatment in breast cancer cells and MDA-MB-231 xenograft mouse models. IS20 can be used for cancers research.
Cat.No	DC79101
Name	IS20

Chemical Properties

CAS	324561-95-7
Formula	C23H21N3O3
MW	387.43
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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