IS811 Datasheet DC Chemicals

Description	IS811 is a potent, selective CCR3 antagonist with IC50 of 2.0 nM, potently inhibits chemotaxis with EC50 of 19 nM.IS811 displays >100-fold selectivity over 5-HT2a, DAT and NET.IS811 (0-20 mg/kg) dose-dependently inhibited eotaxin-induced eosinophil influx to the lung in vivo.
Cat.No	DC70517
Name	IS811

Chemical Properties

CAS	276698-73-8
Formula	C27H36FN3O2
MW	453.602
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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