Ivarmacitinib free base Datasheet DC Chemicals
Description Ivarmacitinib, also known as SHR0302, is a novel potent JAK inhibitor which blocks JAK/STAT3 signaling, suppresses proliferation, migration and collagen production, and induces the apoptosis of hepatic stellate cells. SHR0302 may attenuate the severity of AA rats, partially through reducing Th17 function and total B cell proportion by inhibiting JAK1-STAT3 phosphorylation.
Cat.No DC75748
Name Ivarmacitinib free base

Chemical Properties

CAS 1445987-21-2
Formula C18H22N8O2S
MW 414.488
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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