JNJ10191584 Datasheet DC Chemicals

Description	JNJ10191584 (VUF6002) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 shows 540-fold selectivity to H4 receptor over H3 receptor with a Ki value of 14.1 μM. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively.
Cat.No	DC72335
Name	JNJ10191584

Chemical Properties

CAS	73903-17-0
Formula	C13H15N4OCL
MW	278.7374
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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