JP-2-249 Datasheet DC Chemicals
Description JP-2-249 functions as a molecular glue degrader that selectively targets SMARCA2 for proteasomal degradation. In MV-4-11 leukemia cells, treatment with JP-2-249 (1–10 μM) induces dose-dependent reduction of SMARCA2 protein levels, demonstrating potent degradation activity.
Cat.No DC67377
Name JP-2-249

Chemical Properties

CAS 3036530-41-0
Formula C25H25N5O4
MW 459.50
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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