JPS014 Datasheet DC Chemicals

Description	JPS014 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS014 degrades class I histone deacetylase (HDAC). JPS014 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells.
Cat.No	DC71066
Name	JPS014

Chemical Properties

CAS	2669785-76-4
Formula	C46H59N7O7S
MW	854.07
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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