JTE-607 dihydrochloride Datasheet DC Chemicals

Description	Cytokine release inhibitor, inhibiting production of IL-1ß, IL-8, IL-6, IL-10 and TNFalpha
Cat.No	DC43188
Name	JTE-607 dihydrochloride

Chemical Properties

CAS	188791-09-5
Formula	C25H31N3O5CL2.2[HCL]
MW	597.35862
Storage	0°C (short term), -20°C (long term), desiccated

References

[1]. M Kakutani, et al. JTE-607, a novel inflammatory cytokine synthesis inhibitor without immunosuppression, protects from endotoxin shock in mice. Inflamm Res. 1999 Aug;48(8):461-8. [2]. Nathan T Ross, et al. CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nat Chem Biol. 2020 Jan;16(1):50-59.

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