Description
Keliximab (SB-210396) is a chimeric human/macaque IgG1 anti-CD4 monoclonal antibody with a Ki value of 1.0 nM for soluble CD4. Keliximab blocks T cell proliferation and inhibits IL-2 production. Keliximab can be used for cancer research.
Cat.No
A1035
Name
Keliximab
Chemical Properties
CAS
174722-30-6
Synonyms
Immunoglobulin G1,anti-(human CD4 (antigen)) (human-Macaca monoclonal CE9.1 g1-chain), disulfide withhuman-Macaca monoclonal CE9.1 l-chain, dimer;Immunoglobulin G1,anti-(human CD4 (antigen)) (human-Macaca monoclonal CE9.1 g1-chain), disulfi...;Immunoglobulin G1,anti-(human CD4 (antigen)) (human-Macaca monoclonal CE9.1 g1-chain), disulfide withhuman-Macaca monoclonal ;IDEC CE91;Immunoglobulin G 1 (human-Macaca monoclonal CE91 gamma1-chain anti-human antigen CD 4), disulfide with human-Macaca monoclonal CE91 lambda-chain, dimer;Immunoglobulin G1, anti-(human CD4 (antigen)) (human-macaca monoclonal CE9.1 gamma1-chain disulfide with human-macaca monoclonal CE9.1 lambda-chain, dimer;Immunoglobulin G1, anti-(human CD4 (antigen)) (human-Macaca monoclonal CE91 gamma1-chain), disulfide wi;Keliximab [INN];Keliximab;Immunoglobulin G1, anti-(human cd4 (antigen)) (human-macaca monoclonal ce91 gamma1-chain), disulfide with human-macaca monoclonal ce91 lambda-chain, dimer;Idec ce91;Immunoglobulin G 1 (human-macaca monoclonal ce91 gamma1-chain anti-human antigen cd 4), disulfide with human-macaca monoclonal ce91 lambda-chain, dimer;Keliximab [inn];Research Grade Keliximab
pH value
Corresponds to reference standard: PASS
Non-reduced CE-SDS
>95%
SEC-HPLC
>95%
Isoelectric Point
Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard: PASS
References
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