KNa1.1 inhibitor 31 Datasheet DC Chemicals

Description	KNa1.1 inhibitor 31 is a potent, selective, orally available inhibitor of sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) with IC50 of 40 nM (hKNa1.1 WT).KNa1.1 inhibitor 31 reduced seizures and interictal spikes in a mouse model of KCNT1 GoF.
Cat.No	DC70542
Name	KNa1.1 inhibitor 31

Chemical Properties

CAS	2540502-26-7
Formula	C16H12F6N6O2
MW	434.302
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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