LCL-ER(dec) Datasheet DC Chemicals
Description LCL-ER(dec) is a potent and selective oligonucleotide-type degrader via targeting transcription factor (TFs). The main target of LCL-ER(dec) is SNIPER (specific and non-genetic inhibitor of apoptosis protein [IAP]-dependent protein erasers). LCL-ER(dec) selectively degrades ERα (estrogen receptor α) via the UPS (ubiquitin-proteasome system) with an IC50 of 31.2 μM. LCL-ER(dec) is applicable to the development of other oligonucleotide-type degraders that target different TFs.
Cat.No DC48374
Name LCL-ER(dec)

Chemical Properties

CAS
Formula
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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