LY3502970 (Orforglipron) Datasheet DC Chemicals

Description	LY-3502970 (Orforglipron) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor.LY3502970 is a partial agonist, biased toward G protein activation over β-arrestin recruitment at the GLP-1R.
Cat.No	DC70577
Name	LY3502970 (Orforglipron)

Chemical Properties

CAS	2212020-52-3
Formula	C48H50F2N10O5
MW	884.971416950226
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Pyrazolopyridine derivative having glp-1 receptor agonist effect. WO2013046136A1. [2]. Kawai T, Sun B, Yoshino H, et al. Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist. Proc Natl Acad Sci U S A. 2020;117(47):29959-29967.

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