MCI-INI-3 Datasheet DC Chemicals

Description	MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM), shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity).MCI-INI-3 also displays on inhibition against six isoforms of ALDH (ALDH16A1, ALDH7A1, ALDH9A1, ALDH2, ALDH1B1, ALDH18A1).MCI-INI-3 demonstrates selective binding to ALDH1A3 in glioma stem cell lysates, inhibits ALDH activity and affects RA synthesis in cells.
Cat.No	DC70590
Name	MCI-INI-3

Chemical Properties

CAS	1011366-31-6
Formula	C21H15N3O4
MW	373.36
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

1. Jianfeng Li, et al. Commun Biol. 2021 Dec 21;4(1):1420.

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