ML381 fumarate Datasheet DC Chemicals

Description	ML381 (VU0488130) is a highly mAChR subtype selective M5 orthosteric antagonist with IC50/Ki of 450/340 nM for hM5, has no inhibitory activity on hM1-4 (IC50>30 uM); exhibits good DMPK properties and CNS penetration (B:P ratio of 0.58) to support both in vitro and in vivo studies.
Cat.No	DC70606
Name	ML381 fumarate

Chemical Properties

CAS
Formula	C25H25N3O8
MW	495.488
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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