Nafarelin Datasheet DC Chemicals
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Cat.No DC65644
Name Nafarelin

Chemical Properties

CAS 76932-56-4
Formula C66H83N17O13
MW 1322.4713
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：76932-56-4
Product Name：Nafarelin
Synonyms：Nafarelin;(D-2-Nal?)-LHRH;(D-2-Nal⁶)-LHRH;Nafarelin Acetate;Nacenyl;NAF;Nafareline;Nasanyl;Synarel;Synrelina;Luteinizinghormone-releasing factor (pig), 6-[3-(2-naphthalenyl)-D-alanine]-;NAG;[6-D-(2-naphthyl)-alanine]LH-RH;26: PN:WO2007012430 SEQID: 28 claimed protein;Nafarelinum;Nafarelina;Nafarelinum [Latin];Nafareline [French];Nafarelina [Spanish];Nafarelin [INN:BAN];1X0094V6JV;LHRH, Ala(2-naphthyl)(6)-;6-(3-(2-Naphthalenyl)-D-alanine)luteinizing hormone-releasing factor (pig);C66H83N17O13;BIDD:GT0760;BDBM84707;Luteinizing hormone-releasing factor (pig), 6-(3-(2-naphthalenyl)-D-alanine)-;DB00666;K335;932N564;Luteinizing hormo
EINEC:
Molecular Formula：C66H83N17O13
Molecular Weight：1322.4713
Target: GnRH
In Vivo
In Vitro Nafarelin is a gonadotropin-releasing hormone (GnRH) agonist that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1]. Nafarelin is used effectively in in vitro fertilisation programmes. Nafarelin is readily and rapidly absorbed following intranasal delivery, and is protected to some extent from enzymatic degradation GnRH.
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Letassy NA et al. Nafarelin acetate: a gonadotropin-releasing hormone agonist for the treatment of endometriosis. DICP. [2]. Chrisp P et al. Nafarelin. A review of its pharmacodynamic and pharmacokinetic properties, and clinical potential in sex hormone-related conditions.Drugs.
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