Nav1.7-IN-8 Datasheet DC Chemicals

Description	Nav1.7-IN-8 is a potent blockage of NaV1.7 with high selectivity for the inhibition of NaV1.7 over the subtypes hNaV1.1 and hNaV1.5. Nav1.7-IN-8 inhibits CYP2C9 and CYP3A4 with an IC50 of 0.17 μM and 0.077 μM, respectively. Nav1.7-IN-8 displays significant analgesic effects in rodent models of acute and inflammatory pain.
Cat.No	DC45807
Name	Nav1.7-IN-8

Chemical Properties

CAS	1432913-44-4
Formula	C21H12CLF2N5O4S2
MW	535.93
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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