Neratinib Datasheet DC Chemicals

Description	Neratinib, also known as HKI-272 or PB272, is an orally available, irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor.
Cat.No	DC75083
Name	Neratinib

Chemical Properties

CAS	698387-09-6
Formula	C30H29CLN6O3
MW	557.04
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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