NIC-0102 Datasheet DC Chemicals

Description	NIC-0102 is an orally active proteasome inhibitor (pIC50=7.55) that specifically inhibits NLRP3 inflammatory vesicle activation. NIC-0102 shows potent anti-inflammatory effects in a model of dextran sulfate sodium (DSS)-induced ulcerative colitis. NIC-0102 also inhibits production of pro-IL-1β.
Cat.No	DC72096
Name	NIC-0102

Chemical Properties

CAS	2806031-94-5
Formula	C21H25BF2N2O4
MW	418.24
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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