NIC-12 Datasheet DC Chemicals
Description NIC-12 is a potent NLRP3 inhibitor. NIC-12 selectively reduces circulating IL-1ß levels in the LPS-endotoxemia mice model. NIC-12 inhibits NLRP3 inflammasome activation in mouse macrophages.
Cat.No DC75890
Name NIC-12

Chemical Properties

CAS 2409826-23-7
Formula C22H28CLN5O2S
MW 462.01
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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