Nimotuzumab Datasheet DC Chemicals

Description	Nimotuzumab is a humanized IgG1 monoclonal antibody targeting EGFR with a KD of 0.21 nM. Nimotuzumab is directed against the extracellular domain of the EGFR blocking the binding to its ligands. Nimotuzumab, a strong antitumor agent, is cytolytic on target tumors by its capacity to cause antibody dependent cell mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC).
Cat.No	A904
Name	Nimotuzumab

Chemical Properties

CAS	780758-10-3
Synonyms	h-R3;Theraloc;TheraCIM h-R 3;TheraCIM;RadioTheraCIM;Nimotuzumab;DiaCIM
pH value	Corresponds to reference standard: PASS
Non-reduced CE-SDS	>95%
SEC-HPLC	>95%
Isoelectric Point	Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality	Corresponds to reference standard: PASS
Peptide mapping	Corresponds to reference standard: PASS
N-terminal sequence	Corresponds to reference standard: PASS

References

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