Niraparib HCl Datasheet DC Chemicals

Description	Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway.
Cat.No	DC75114
Name	Niraparib HCl

Chemical Properties

CAS	1038915-64-8
Formula	C19H21CLN4O
MW	356.854
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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