NP3-562 Datasheet DC Chemicals
Description NP3-562 is a potent, orally bioavailable, tricyclic NLRP3 inhibitor with IC50 of 0.26 μM in the FP binding assay. NP3-562 demonstrates excellent potency in human whole blood and full inhibition of IL-1β release in a mouse acute peritonitis model.
Cat.No DC60542
Name NP3-562

Chemical Properties

CAS
Formula C19H24CLN5O3S
MW 437.94
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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