ODN 2216 Datasheet DC Chemicals

Description	ODN?2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. ODN?2216 induces high amounts of IFN-α and IFN-β. ODN 2216 induces IFN-α by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). ODN 2216 stimulates IFN-γ production in peripheral blood mononuclear cells (PBMC), which is indirect and mediated by IFN-α/β. ODN 2216 can activate NK cells and promote IFN-γ production of TCR-triggered CD4+ T cells. The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN 2216 sodium) that retains the same biological activity.
Cat.No	DC67266
Name	ODN 2216

Chemical Properties

CAS	332437-00-0
Formula
MW	6432.00
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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