OTSSP167 free base Datasheet DC Chemicals
Description OTSSP167, also known as OTS167, is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167 binds to MELK, which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK-expressing tumor cells.
Cat.No DC75513
Name OTSSP167 free base

Chemical Properties

CAS 1431697-89-0
Formula C25H28CL2N4O2
MW 487.425
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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