Pelcitoclax Datasheet DC Chemicals

Description	Pelcitoclax, also known as APG 1252 and BM1251, is a potent and selective Bcl-2/Bcl-XL inhibitor. APG-1252 A Bcl-2 homology (BH)-3 mimetic and selective inhibitor of the anti-apoptotic proteins B-cell lymphoma 2 (Bcl-2) and Bcl-XL, with potential pro-apoptotic and antineoplastic activities. Upon administration, Bcl-2/Bcl-XL inhibitor APG-1252 specifically binds to and inhibits the activity of the pro-survival proteins Bcl-2 and Bcl-XL. This restores apoptotic processes and inhibits cell proliferation in Bcl-2/Bcl-XL-dependent tumor cells.
Cat.No	DC60513
Name	Pelcitoclax

Chemical Properties

CAS	1619923-36-2
Formula	C57H66CLF4N6O11PS4
MW	1281.8479
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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