PF-06446846 HCl Datasheet DC Chemicals
Description PF-06446846 is a selective orally active PCSK9 inhibitor that appears to act by causing the ribosome to stall when synthesizing PCSK9. PCSK9 binds to the LDL receptor, preventing it from removing LDL cholesterol from the blood. PF-06446846 was found to reduce plasma PCSK9 and total cholesterol levels in rats.
Cat.No DC75061
Name PF-06446846 HCl

Chemical Properties

CAS 1632250-50-0
Formula C22H21CL2N7O
MW 470.358
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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