PF-06648671 Datasheet DC Chemicals
Description PF-06648671 is a potent γ-secretase modulator with IC50 of 8.9 nM against Aβ42. PF-06648671 has favorable brain availability in rodent, which translated into excellent central exposure in human and robust reduction of amyloid β (Aβ) 42 in cerebrospinal fluid (CSF).
Cat.No DC21501
Name PF-06648671

Chemical Properties

CAS 1587727-31-8
Formula C25H23CLF4N4O3
MW 538.928
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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