PF-3758309 dihydrochloride Datasheet DC Chemicals

Description	PF-3758309 dihydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 dihydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation.
Cat.No	DC46430
Name	PF-3758309 dihydrochloride

Chemical Properties

CAS
Formula	C25H32CL2N8OS
MW	563.55
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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