PLN-1474 Datasheet DC Chemicals
Description PLN-1474 (compound 1) is an orally active and selective avß1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or treating a fibrotic or cirrhotic disease or disorder.
Cat.No DC72321
Name PLN-1474

Chemical Properties

CAS 2408065-32-5
Formula C24H37N3O4
MW 431.57
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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