PLX5622 free base Datasheet DC Chemicals

Description	PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor. PLX5622 has been shown to eliminate microglia from the brain, which can be sustained in wild-type and the Alzheimer's disease model mice (3xTg-AD model). In the AD model PLX5622 prevents microglial association with amyloid β plaques and improves cognition.
Cat.No	DC75804
Name	PLX5622 free base

Chemical Properties

CAS	1303420-67-8
Formula	C21H19F2N5O
MW	395.41
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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