PRC2 EED-IN-1 Datasheet DC Chemicals
Description PRC2 EED-IN-1 is a potent, selective, allosteric, orally bioavailable inhibitor of the EED subunit of histone methyltransferase PRC2 with IC50 of 44 nM (H3K27me3 inhibition).PRC2 EED-IN-1 retains efficacy against EZH2 inhibitor-resistant cell lines (Karpas 44 cell IC50=27 nM), exhibits in vivo efficacy in EZH2-driven tumors in vivo.
Cat.No DC70707
Name PRC2 EED-IN-1

Chemical Properties

CAS 2762275-20-5
Formula C19H19FN8O
MW 394.414
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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