PROTAC AR-V7 degrader-1 Datasheet DC Chemicals

Description	PROTAC AR-V7 degrader-1 (Compound 6) is a potent, orally bioavailable and selective AR-V7 degrader with the DC50 of 0.32 µM by recruiting VHL E3 ligase to Androgen receptor (AR) DNA binding domain (DBD) binder. PROTAC AR-V7 degrader-1 exhibits activity against 22Rv1 cell-line expressing AR-V7 with the EC50 of 0.88 µM.
Cat.No	DC50136
Name	PROTAC AR-V7 degrader-1

Chemical Properties

CAS
Formula	C41H52N6O6S2
MW	789.02
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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