PT-179 Datasheet DC Chemicals

Description	PT-179 is a novel orthogonal immunomodulatory drug (IMiD) derivative that selectively binds to CRBN without inducing degradation of off-target proteins. It demonstrates potent activity in degrading proteins fused to SD40, regardless of whether the fusion occurs at the N or C terminus.
Cat.No	DC60559
Name	PT-179

Chemical Properties

CAS	2924858-25-1
Formula	C17H17N3O5
MW	343.333984136581
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

Continuous evolution of compact protein degradation tags regulated by selective molecular glues-Science . 2024 Mar 15;383(6688):eadk4422. doi: 10.1126/science.adk4422. Epub 2024 Mar 15.

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