GDC-1971 Datasheet DC Chemicals

Description	GDC-1971 showed outstanding potency in biochemical and cell models, and it had a predicted human PK profile that suggested it would achieve target engagement at reasonable doses. GDC-1971 showed an IC50 below the limit of detection of the assay (≪0.001 μM), while that IC50 shifted to 0.17 μM in the same biochemical assay with the constitutively active E76K SHP2 mutant.
Cat.No	DC50265
Name	GDC-1971

Chemical Properties

CAS	2377352-49-1
Formula	C25H26N8O
MW	454.53
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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