(R)-HTS-3 (GLXC-25878) Datasheet DC Chemicals

Description	(R)-HTS-3 (GLXC-25878) is a potent, selective, and cell-active inhibitor of lysophosphatidylcholine acyltransferase 3 (LPCAT3) with an IC50 of 0.09 µM, an enzyme critical for synthesizing C20:4-containing phospholipids. It reduces arachidonic acid-d8 incorporation into phospholipids and mitigates RSL3-induced ferroptosis in HT-1080 and 786-O cancer cells.
Cat.No	DC75866
Name	(R)-HTS-3 (GLXC-25878)

Chemical Properties

CAS	2771208-83-2
Formula	C17H18F2N2O
MW	304.34
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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