(R,R)-VRT-534 Datasheet DC Chemicals
Description (R,R)-VRT-534 is the (R,R)-enantiomer of VRT-534). VRT-534 (Compound 3) is a chemical chaperone targeting connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. Vrt-534 can be used in research related to hearing impairment.
Cat.No DC79002
Name (R,R)-VRT-534

Chemical Properties

CAS 926664-33-7
Formula C25H24CLN3O4S
MW 497.99
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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