RAF-IN-1 Datasheet DC Chemicals
Description RAF-IN-1 is a potent b/cRAF inhibitor with an IC50s of 3.8 nM, 36 nM, 29.4 nM for cRAF, bRAFwt, and bRAFV600E. RAF-IN-1 shows cell growth inhibition with GI50s of 3.4 and 2.9 nM for H358 and A375 cell line bearing bRAFV600E mutation, respectively.
Cat.No DC70038
Name RAF-IN-1

Chemical Properties

CAS 2695505-82-7
Formula C26H22F3N3O4
MW 497.47
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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