RMC6236 Datasheet DC Chemicals
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Cat.No DC65716
Name RMC6236

Chemical Properties

CAS 2765081-21-6
Formula C44H58N8O5S
MW 811.046928882599
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：2765081-21-6
Product Name：RAS-IN-2
Synonyms：RMC6236;RAS-IN-2
EINEC:
Molecular Formula：C44H58N8O5S
Molecular Weight：811.046928882599
Target: KRas G12D
In Vivo
In Vitro RAS-IN-2 (Compound A122) (5 days) 抑制 AsPC-1 (K-Ras G12D) 的细胞活力，IC50 为 1-10 μM.
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Ethan AHLER, et al. Use of sos1 inhibitors to treat malignancies with shp2 mutations. Patent WO2022060583A1.
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