RMC-6291 Datasheet DC Chemicals

Description	RMC-6291 is a potent covalent inhibitor of KRASG12C(ON) that forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA). RMC-6291 overcomes limitations of first-generation KRASG12C(OFF) inhibitors in preclinical models by directly targeting the active form of this important oncogenic driver.
Cat.No	DC60452
Name	RMC-6291

Chemical Properties

CAS	2641998-63-0
Formula	C55H78FN9O8
MW	1012.26173734665
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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