Sacubitril calcium salt Datasheet DC Chemicals

Description	Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
Cat.No	DC75302
Name	Sacubitril calcium salt

Chemical Properties

CAS	1369773-39-6
Formula	C48H56CAN2O10
MW	861.06
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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