SEL120-34A HCl Datasheet DC Chemicals

Description	SEL120-34A is a potent and selective CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains. EL120-34A inhibits phosphorylation of STAT1 S727 and STAT5 S726 in cancer cells in vitro. Consistently, regulation of STATs- and NUP98-HOXA9- dependent transcription has been observed as a dominant mechanism of action in vivo.
Cat.No	DC75357
Name	SEL120-34A HCl

Chemical Properties

CAS	1609452-30-3
Formula	C15H19BR2CLN4
MW	450.603
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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