Selisistat racemate Datasheet DC Chemicals

Description	Selisistat racemate is a racemic mixture of EX-527, an inhibitor of sirtuin 1 (SIRT1; IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7 cells.
Cat.No	DC75326
Name	Selisistat racemate

Chemical Properties

CAS	848193-68-0
Formula	C13H13CLN2O
MW	248.71
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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